The following are the most frequently asked questions about Align products and probiotics for healthcare professionals.

Q. What is Align?

A. Align is a daily probiotic supplement that helps support gastrointestinal health. Align Digestive Support (Bifidobacterium 35624™) helps relieve and manage IBS symptoms. For more information about IBS, see our mini video series available on our product information page.

Q. How does Align work?

A. Align supplements the digestive system with good bacteria to help promote and support a healthy digestive system and maintain digestive health.

Q. What is Bifidobacterium 35624?

A. Bifidobacterium 35624 is the trademarked name for the natural probiotic ingredient found in Align Digestive Support. To see why strain specificity is important click here

Q. How many bacteria are in each capsule/chewable of Align?

A. Each Align Digestive Support capsule/chewable contains at least 1 x 109 (one billion) live beneficial bacteria/CFU when manufactured and provides an effective level of bacteria (1x 107 CFU) until at least the “best by” date. Each Align Antibiotic Support capsule contains 1x1010 (ten billion) live beneficial bacteria/CFU of Saccharomyces boulardii CNCM I-1079 at the time of manufacture and contains an effective level of probiotic bacteria throughout the shelf life of the product.

Q. Is a higher CFU count better?

A. No. According to the International Scientific Association for Probiotics and Prebiotics (ISAPP), different probiotics have been shown to be effective at various levels. A product with a larger dose is not always better. The dose should match studies demonstrating their benefit(s), which typically ranges from 100 million – 10+ billion cfu/dose.1

Q. How long does it take for probiotics to work?

A. The time-to-effect of probiotics depends on a person’s gut flora and the specific strain of the probiotic supplement. Align Digestive Support should be taken once daily on a consistent basis to maximize results. Align Antibiotic Support (Saccharomyces cerevisiae var. boulardii CNCM I-1079) should be taken 2 times daily, while on antibotics.

Q. Does Align have any side effects?

A. In clinical studies, there was no significant difference in side-effects between Align Digestive Support and placebo. Side effects, if present, tend to be mild. Some patients experience gas and/or bloating in the first few weeks. This may be temporary, while their digestive system adjusts to Align.

Q. What’s the difference between Align Digestive Support Capsules and Chewables?

A. Align Digestive Support Chewables contain the same effective probiotic strain as Align Digestive Support Capsules but in a great-tasting Strawberry & Banana Smoothie flavoured chewable tablet.

Q. How do you take Align?

A. Align can be taken at any time of day, with or without food. We recommend that patients take it as part of their daily routine, at a time that will be easy to remember.

Q. Are there any restrictions on how to take Align?

A. No, Align Digestive Support is designed to be taken once daily, as part of a healthy lifestyle, with no restrictions.

Q. Should Align be refrigerated?

A. Align does not need to be refrigerated. Patients can take it any time or anywhere that’s convenient.


  1. International Scientific Association for Probiotics and Prebiotics (ISAPP) Probiotic Checklist: Making a Smart Selection.


Among Doctors and Gastroenterologists who recommended a brand of probiotic in ProVoice™ surveys 2015 to 2021.